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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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RayBiotech inc mouse cytokine antibody array 1 kit
FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of <t>cytokine</t> expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all <t>analyzed</t> <t>cytokines.</t> (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).
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Image Search Results


FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of cytokine expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all analyzed cytokines. (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).

Journal: Glia

Article Title: Chronically activated microglia in ALS gradually lose their immune functions and develop unconventional proteome.

doi: 10.1002/glia.24531

Figure Lengend Snippet: FIGURE 6 Marked deregulation of innate immune response in chronically activated microglia from SOD1-G93A mice. (a, b) Analysis of cytokine expression in wild type microglia and (b) microglial cells after LPS challenge. Heat map normalized representation of all analyzed cytokines. (c–n) Expression analyses of pro- and anti-inflammatory cytokines 24 h after LPS exposure. (Data are shown as mean ± SEM, with ns >0.5, *p < .05; **p < .01; ***p < .001; n = 3).

Article Snippet: The inflammatory cytokines expression profile was analyzed with a mouse cytokine antibody array (RayBio Mouse Inflammation Antibody Array 1; RayBiotech).

Techniques: Expressing